Growth Hormone (GH) Replacement Therapy in Adult-Onset GH Deficiency

HGH Growth Hormone Medical Studies - Endocrine Care and Human Growth Hormone @ www.HGHnews.us

Endocrine Care – HGH, The Human Growth Hormone

Growth Hormone (GH) Replacement Therapy in Adult-Onset GH Deficiency: Effects on Body Composition in Men and Women in a Double-Blind, Randomized, Placebo-Controlled Trial

Adult GH Deficiency (AGHD) is characterized by an altered body composition, an atherogenic lipid profile, decreased exercise capacity, and diminished quality of life. We performed a randomized, double-blind, placebo-controlled, multicenter study in 166 subjects with AGHD to assess the effects of GH on these outcomes. GH was initiated at 0.0125 mg/kg·d, increased to 0.025 mg/kg·d as tolerated, or decreased to 0.00625 mg/kg·d for 12 months. Primary measures of efficacy included body composition, strength and endurance, and quality of life. Additional parameters included serum IGF-I concentrations, serum lipids, and bone mineral density.

After 12 months, 79% of subjects remained on GH 0.0125 mg/kg·d, whereas 21% received 0.00625 mg/kg·d. GH-treated men and women demonstrated significant decreases in total body and trunk fat and increases in lean body mass over baseline. In GH-treated men, mean IGF-I sd scores exceeded age-adjusted normal ranges, whereas similar doses produced a smaller response in women. GH treatment was associated with significant improvements in total cholesterol and low-density lipoprotein (P < 0.05 for all). No significant treatment effects were observed in strength and endurance, quality of life, or bone mineral density. GH treatment was generally well tolerated. Subjects with AGHD should receive individualized GH therapy to maintain IGF-I between the mean value and +2 sd and improve body composition and cardiovascular risk factors.

GH IS REQUIRED for normal growth and metabolic homeostasis in children. However, GH secretion occurs throughout life and is known to have profound effects on anabolism, lipolysis, and carbohydrate metabolism. Individuals who develop adult GH deficiency (AGHD) secondary to pituitary or hypothalamic disease exhibit abnormal body composition, characterized by a significant increase in fat mass, particularly visceral fat, and a decrease in lean body mass (1, 2, 3, 4, 5, 6). Many have diminished strength and exercise capacity that may improve with GH therapy (7, 8). Adults with AGHD also demonstrate altered lipid metabolism, increased incidence of cardiovascular disease, and diminished quality of life (9, 10, 11, 12). Reduced life expectancy secondary to increased cerebrovascular and cardiovascular disease has also been reported in patients with hypopituitarism (13). Adults with AGHD experience feelings of social isolation, decreased energy, and an overall poorer quality of life when compared with controls (11, 14, 15, 16). Bone mineral density (BMD) is also reduced in these subjects (6), resulting in a 3-fold increase in bone fracture rate (17).

Short-term GH replacement therapy in adults has been associated with beneficial effects on body composition, fat distribution, and quality of life (2, 18, 19). Improvements in bone mineral content and BMD are not apparent until GH has been administered for at least 18 months (20, 21). In general, studies of GH therapy in subjects with AGHD have been relatively small, nonrandomized, or uncontrolled. Moreover, potential differences in the ability of men and women to respond to GH have not been adequately examined in most of these studies.

This large multicenter, randomized, placebo-controlled study explored the effects of GH treatment on body composition and physical performance. The primary end points were a decrease in percentage of body fat, an increase in muscle strength, and improved quality of life. The anticipated reduction in cardiovascular risk emerged as the most compelling reason to examine the impact of GH replacement therapy in adults with GHD.

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Men have a particularly difficult time finding physicians and information regarding male hormone related therapy as the medical community tends to shy away from supporting bio-identical treatments and therapies for men. However, times are changing and many general practitioners now contemplate the advantagous, benefits as well as effects and risks inherent in hormone replacement therapy for men. Click here for a good resource for HGH Therapy for Men to read more…

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The Role of hGH Secretagogues – Growth Hormone

The Role of hGH Secretagogues in Anti-Aging Therapy

Human Growth Hormone is the topic of much debate and research throughout the centuries can be found in the seed of an idea: the reacquisition of youthful qualities. The 21st century is increasing past efforts, spending countless dollars on the development of products to help a youth obsessed society turn back the signs of time.

HGH Research. One of the most promising developments occurred in the 90′s when Dr. Daniel Rudman reported to the New England Journal of Medicine that he had reversed aging through the use of human growth hormone (hGH) injections. The most promising research today now focuses on hGH precursors known as secretagogues.

Secretagogues are substances known for their ability to cause other substances to be secreted. In this case, it is the pituitary gland in need of stimulating with regards to the release of hGH (a hormone known as somatropin). Researchers James Jamieson and L.E. Dorman, D.O. focused their research on secretagogues known for their ability to reverse the condition of somatopause (hGH deficiency) by naturally stimulating the release of growth hormones. They found safe biological activators comprised mainly of specific amino acids, proteins and botanical extracts, which stimulated certain receptors in the pituitary and hypothalamus glands.

HGH Declines. Although the human body does experience decline in its release of hGH at a rate of about 14% per decade, your pituitary gland continues to produce hGH well into your 70′s and 80′s. However, there are a number of factors which begin to interfere with production, and this may be where the most progress could be made.

HGH

Bi-weekly fasting

Many longevity experts recommend fasting on a regular basis. Fasting should not occur more often than once every two weeks, and for no longer than 24 hours. The reason fasting encourages the release of hGH is because the highest levels of growth hormone are released while we sleep, and more so, following a fast of 24 hours.

Consume a diet low on the glycemic index

Another way to boost the release of growth hormone levels is to eat a diet which is low on the glycemic index: avoiding foods like pasta, potatoes and refined sugars. The rapid increase in blood sugar experienced when eating these foods stimulates the production of insulin. This increase of insulin in the blood causes your body to produce a chemical called somatostatin, known to suppress hGH release.

Fast for two hours before exercise

It is also helpful to exercise on an empty stomach, fasting for two hours before working out. Regular exercise which utilizes both cardio fitness and strength training stimulates your pituitary gland to increase levels of growth hormone levels. Insulin levels in the blood will act to suppress exercise induced release of hGH, causing you to not get the full range of benefits available when working out.

Reduce fat intake

Reducing fat intake is also useful in the quest for increased circulation of growth hormones in the body. Dietary fat acts to block both the production and release of hGH. Optimal level of fat intake is between 20 and 30 percent of your daily caloric intake. These fats should come from healthy oils such as olive, grape seed and avocado.

Even with the most brilliant scientists working tirelessly to reduce symptoms of aging, eternal youth is impossible. However, there is reason to be optimistic with regards to an increased duration of years of healthy living, clear mind and deftness of physicality. Fitness goals, excellent dietary habits and even the right supplement formula may very well offer something akin to youth.

The Endocrine System – Hormones

The Endocrine System, HGH, Testosterone and other Hormones

The endocrine system is a complex network comprised of integrated hormone-producing glands and organs. Its function, like that of the nervous system, is communication throughout the body. The endocrine system produces and releases different types of hormones to maintain and control a number of important functions of the body, including growth and development, metabolism, sexual and reproductive function, organ and tissue function.

A hormone imbalance (either too much or too little hormone production) can have drastic effects on body function and a person’s health. The main purpose of the endocrine system is extracellular (outside the cell) communication; while the nervous system communicates using neurons and electricity, the endocrine or hormonal system uses chemicals, called hormones to communicate between cells and regulate body functions. Hormones use a negative feedback system so that when too much of one hormone is produced another hormone is secreted to counter it. In this way a person’s body maintains the delicate balance of proper hormone levels.

Components of the endocrine system include hormone-producing glands, such as the hypothalamus, pituitary, thyroid, adrenals, testes and ovaries and organs such as the liver, pancreas, and kidneys. Each of the glands and organs in the endocrine system produces different types of hormones that perform different functions. A number of different conditions can affect the way the endocrine system functions. Some of these conditions are natural and our endocrine system functions differently when we age and go through menopause or andropause in men.

There can be a genetic, or hereditary component to the way an individual’s endocrine system works as well. However, a number of external substances can also affect endocrine function. These substances, called environmental endocrine disruptors (EEDs), consist of commercial synthetic chemicals and, although the full effect of their introduction into our environment is unknown, have been linked to birth defects, immune system disorders, neurological changes, and more.

Types of Hormones and What They Do

In order to regulate the myriad functions required for normal bodily function, the glands and organs that comprise the endocrine system create many types of hormones, each with a specific function. Included in the different types of hormones your endocrine system produces are the following:

Vasopressin – Created by the hypothalamus, vasopressin prompts the pituitary gland to release a hormone that helps maintain blood pressure and water and electrolyte balance.

Human Growth Hormone — Growth hormone, HGH or GH is one of the types of hormones produced by the pituitary gland  and one of the most important glands in the endocrine system.  Growth Hormone (GH) stimulates growth during childhood and also stimulates cell reproduction and repair which helps adults maintain energy,  muscle and bone mass.

Testosterone, Progesterone, Estrogen and Oxytocin – are the sex and reproductive hormones responsible for sexual health as well as gender characteristics, muscle, heart, brain and bone health.

Calcitonin — Calcitonin, produced by the thyroid gland, aids in bone construction.

Insulin – Insulin regulates glucose, or sugar intake, by helping it move from the blood into cells. It is one of the types of hormones produced by the pancreas.

Adrenaline – Produced within the adrenal glands (small glands located at the top of each kidney), adrenaline works with noradrenaline to produce the “fight or flight” response by increasing the supply of oxygen to the brain and muscles, dilating the pupils, and suppressing bodily functions not useful in an emergency situation (such as digestion).

Noradrenaline — Noradrenaline works with adrenaline to help the endocrine system produce the “flight or flight” response; in an emergency situation, it boosts the oxygen supply to the brain and the supply of glucose to the muscles.

The endocrine system is one of the body’s main systems for communicating, controlling and coordinating the body’s work. It works with the nervous system, reproductive system, kidneys, gut, liver, pancreas and fat to help maintain and control the following:

  • Body energy levels
  • Sexual Reproduction
  • Growth and Development
  • Internal Balance of Body Systems, called Homeostasis
  • Immuno Responses to Stress and Injury

The endocrine system accomplishes these tasks via a network of glands and organs that produce, store, and secrete certain types of hormones. Hormones are special chemicals that move into body fluid after they are made by one cell or a group of cells. Different types of hormones cause different effects on other cells or tissues of the body using receptor cells that accept the “signals” of their respective hormone “messengers”.

Endocrine glands and endocrine-related organs are like factories. They produce and store hormones and release them as needed. When the body needs these substances, the bloodstream carries the proper types of hormones to specific targets. These targets may be organs, tissues, or cells. To function normally, the body needs glands that work correctly, a blood supply that works well to move hormones through the body to their target points, receptor places on the target cells for the hormones to do their work, and a system for controlling how hormones are produced and used.

Hormone Imbalance

Each of the many types of hormones fulfills a specific function by signaling a different message to the cells, tissues, or organs involved. A hormone imbalance, a situation in which there is too much or too little of a specific hormone, can result in a number of different endocrine system disorders, some more serious than others.

Diabetes – Diabetes is one of the more serious results of hormone imbalance in that, if it is left undiagnosed and/or untreated, it can result in blindness, heart disease, kidney failure, and death. Diabetes occurs when the pancreas either produces too little insulin or does not effectively use the insulin it does produce. Insulin is the hormone that helps the body process sugar in the bloodstream.

Growth Disorders — Your pituitary gland, also referred to as the “Master Gland” of the endocrine system, produces growth hormone (GH) which, in the proper levels, stimulates and regulates growth throughout the body. A growth hormone imbalance can, in the event of too much growth hormone, cause gigantism in children and acromegaly in adults; a hormone imbalance in which the endocrine system produces too little GH can result in growth hormone deficiency (GHD), which can lead to stunted growth in children and symptoms such as decreased muscle and bone mass in adults.

Other Disorders – There are more than 6,000 known endocrine system disorders caused by hormone imbalance; for information about these rare, or “orphan,” diseases, please visit our resources page for rare conditions. A dangerous and potentially fatal hormone imbalance can also be caused by steroid abuse which has become a growing problem among body-builders, athletes and some high school-aged youth. The use of anabolic steroids–which should only be taken under the direction of a health professional–is increasing among both men and women. At that time of development the endocrine system is working to bring about a number of changes, both physical and mental, and young athletes may be tempted to use steroids to increase their athletic ability and body image.

HGH – The Elixir of Youth

HGH – is Human Growth Hormone -
the new elixir of youth?


Growth Hormone is said to boost memory and libido – and reverse aging, but as women AND men inject Human Growth Hormone…

Having recently passed his 40th birthday, Graham Marks was beginning to notice how the years were taking their toll.

Despite being a dedicated gym-goer, he had started to put on weight and found his energy levels flagging. But the final straw came when he tore a ligament in his leg. Doctors told him it would take him three months of wearing a brace before he would recover.

Unhappy about such a long lay-off,  Graham, who runs a successful electronics business in the South of England, turned to the other men in his gym for advice on how to speed up the healing process. Almost unanimously, they suggested he did what they did — start injecting himself with a substance called human growth hormone (HGH).

HGH Injections in pursuit of youth: Injecting HGH at HGHnews.us



More and more people are using HGH, the Human Growth Hormone in pursuit of youth. Naturally made in the pituitary gland, the hormone stimulates growth. In the past, it was harvested from corpses before being injected into below-average-height children. Now synthesized in laboratories, it is being used in ways never originally intended.

‘I found some for sale on the internet, bought it and started taking it,’ he says. ‘And my leg recovered in just six weeks.’

That was 18 months ago and Graham hasn’t looked back. He was so impressed by the effect it had on his body that he injects himself with £10 worth of the drug every single day. In that time, he has lost two-and-a-half-stone in weight and put on a noticeable amount of muscle. But, he says, there is more.

‘In my opinion, HGH is a miracle drug. When used in moderation, it will slow down aging in the body. And it helps to heal everything quicker. Last year, when the bad flu went around, I had friends who were ill with it for up to two weeks. I caught it and recovered in a few days.’

On top of that, he noticed an increase in his sexual libido and improvement in the condition of his skin. A friend who is also using it reported that his thinning hair had started to re-grow.

They are extraordinary claims and ones that are echoed not only in the world of muscle-bound fitness-fanatics but  also among those who simply want to halt the body’s aging process in its tracks.

Earlier this summer, singer Robbie Williams admitted he had consulted doctors in LA about taking HGH simply so he could look and feel younger.

‘It’s what all the old fellas are on in LA — it makes them look 40 instead of 60,’ said Williams, who is 37. ‘It’s improving their health, their memory, their hair and skin.’ (In the end, the singer opted for a course of testosterone injections instead.)

Singers looking for a miracle: Robbie Williams admits to having consulted doctors about using HGH and Madonna is rumored to have used it

Women, too, are flocking to try out what has been dubbed ‘cosmetic surgery in a syringe’. The youthful-looking trio of Demi Moore, Jennifer Aniston and Madonna are all rumored to have had HGH jabs.

Dr Lionel Bissoon is one of America’s leading anti-aging gurus. The rich and famous queue up at his New York clinic to be treated with the drug.

‘For many, this is the fountain of youth and it’s very, very popular,’ he says. ‘My patients say they look good, feel strong and even sleep better. Very few people are disappointed.’

Of course, the ministrations of Dr Bissoon do not come cheap: regular treatment can cost up to £1,200 a month. And therein lies the rub. The vast majority of those using HGH both here and in America cannot afford such costs. Instead, they purchase it over the internet from foreign-based websites and then inject themselves.

In so doing, they blindly trust that what they are sent actually does contain some HGH — rather than being counterfeit or contaminated with unknown substances that could harm or even kill them.

But that isn’t the only risk. HGH is not licensed as an anti-aging drug. While some studies have suggested it can help the body heal itself and improve athletic performance, other experts believe its anti-aging abilities have been wildly exaggerated.Worse still, there are growing concerns about the dangers that HGH may pose to health.

Studies show that high levels can lead to swelling of the soft tissues in the body; abnormal growth of the hands, feet and face; high blood pressure; blood clots; diabetes; increased sweating; and excessive hair growth.

Organs — including the heart, liver and kidneys — may also undergo excessive growth, leading to potentially life-threatening problems such as cardiomyopathy, a disease of the heart muscle. Cancer risks are also thought to increase.

Acting young: Jennifer Aniston and Demi Moore are also rumoured to have used HGH to make them look younger

Given that, many will be surprised at just how easy HGH is to obtain in this country.

Manufactured under trade names such as Saizen, Genotropin, Norditropin, Humatrope, Zomacton and Nutropin aq, there are dozens of websites offering it for sale.

The vast majority of these are unregulated and based abroad, thereby sidestepping any risk of prosecution under British laws.

Like steroids, HGH is a class C drug which is illegal to supply. It should only be available from a doctor on prescription to treat severe growth disorders or conditions such as Aids-related muscle wastage. But at the same time, it is not illegal to possess, if possession is for personal use.

In other words, if someone is caught with relatively small amounts of HGH, they are unlikely to have any action taken against them.

And so the internet has become the main channel into the UK and its use — once confined to athletes hoping to gain an illegal edge — has become widespread.

Only last year, a gym in Bristol had to install needle-bins in the men’s toilets because so many people were using the drug (one gym member told how empty vials of HGH had been found on the premises and how he had seen people openly injecting themselves. Syringes had been left in the changing rooms and even on the gym floor.)

Meanwhile, online keep-fit forums are awash with people trading information and advice about the drug.

‘In my opinion, HGH is a miracle drug. When used in moderation, it will slow down ageing in the body. And it helps to heal everything quicker’

Last week, a man calling himself Big Chris posted the following: ‘I’m 21 about 18-19st — that’s fat not muscle. I used to be a bit of a gym buff, 13st of muscle but went to seed when I met my girlfriend. I’ve just started getting back into the gym and I’m considering going on HGH.’

Another wrote: ‘I’m considering getting some HGH — reason being is a few of my fellow gym buddies are on it and say it’s great, they are losing weight and have more energy, fewer aches and pains. What would you expect to pay for HGH? I’m about to pay  for ten days’ supply.’

What this man is about to purchase will no doubt have been imported from abroad. And, more worryingly, he will have no idea as to what it is he is about to start injecting into himself.

The dangers of this Russian roulette approach to self-medication were highlighted last year in a series of raids by police and officers from the Medicines And Healthcare Products Regulatory Agency (MHRA).

Targeting websites selling drugs like HGH, they seized more than £500,000 worth of medicines.

Tests on the confiscated pharmaceuticals showed high levels of counterfeiting and contamination with other drugs, suggesting those making them fail to clean equipment in between manufacturing runs.

‘The dangers of purchasing medicines from an unregulated source are that you just don’t know what you are taking,’ said Mick Deats, MHRA head of enforcement.

‘The dosages could be either too high or too low, contain no pharmaceutical ingredient or a totally different ingredient to that stated. Illegal suppliers have no quality control or standards to abide by.

‘If customers could see the filthy  conditions in which some of these medicines were being transported, stored and handled, they wouldn’t touch them.’

Scalpel or syringe? Using HGH has become seen as a viable alternative to plastic surgery - for men and women. Learn more about Human Growth Hormone and Aging at HGHnews.us - www.hghnews.us



Scalpel or syringe? Using HGH has become seen as a viable alternative to plastic surgery – for men and women

But it is not just gym-users who are taking HGH. The anti-aging industry in the US is worth 88 billion and in the UK worth £300 million a year. As in America, private clinics are offering the drug as a treatment.

The main role of HGH in the body is to boost growth during childhood. As people reach their mid-30s, our natural production of the hormone begins to slow. By topping up those levels, the belief is that the effects of aging can be countered.

While it is not illegal to prescribe drugs such as HGH for conditions for which they were not originally licensed, many doctors, such as Lionel Bissoon, insist they only ever use HGH after extensive blood and hormone tests show there is a deficiency.

But there is still a surprising  reluctance — in this country, at least — to talk about the treatment.

HGH is big news in anti-aging,’ said a Surrey-based doctor whose website advertises the anti-ageing benefits of HGH, but who asked not to be named.

‘But I won’t use it for anyone who isn’t actually deficient in it. To establish that means expensive blood tests, which will cost the patient over £500.

‘After that, if you have a dose of 0.4mg a day, it will cost about £500 a month, possibly up to £1,000 depending on the practitioner. After that, you will need frequent monitoring, which means more blood tests — and more money. It can run into thousands a year.

‘Most people who call me are taken aback by the price. They tell me they can get it much cheaper on the internet but, as I tell them, if they buy from anyone who isn’t a genuine medical doctor, which I am, they don’t know what they are getting into.’

‘It certainly didn’t make me look any younger. But even the positive effects were temporary. I lost some fat, but not my wrinkles. My feeling is that the benefits have been exaggerated’

One person who has first-hand experience of its effects is Dr Cecilia Tregear, a Harley Street medic who specializes in hormone treatments.

‘I took HGH several years ago,’ she admits. ‘I tried it when I turned 50 to find out if all the fuss was justified. What I noticed were initial, apparently positive effects on my energy levels and my libido rather than physical changes.

‘It certainly didn’t make me look any younger. But even the positive effects were temporary. I lost some fat, but not my wrinkles. My feeling is that the benefits have been exaggerated.’

Her view is backed up by a review of all the research into HGH conducted by scientists at Stanford University in California in 2007. It concluded that using the growth hormone resulted in small changes in body composition and an increased likelihood of conditions such as diabetes.

‘On the basis of this evidence,’ said the review, ‘growth hormone cannot be recommended as an anti-ageing therapy.’

But words such as that are unlikely to carry much truck with the likes of Graham Marks who believe that, in HGH, they have found the secret to eternal youth.

‘I know that I’m never going to be young again, but this stuff keeps me younger longer,’ he says. ‘I honestly feel it has taken at least a decade off my body age.’

But could it actually end up taking years off his life? It is something that he and the others taking part in this dangerous experiment will only discover when it is too late.

You may have searched for HGH in the News, HGH News, HGH Treatments, HGH Therapy, Somatropin Injections, HGH Injections, Human Growth Hormone, Aging and HGH, Growth Hormone and Anti-Aging.

The HCG Diet Plan is also becoming a common place hormone therapy. Many age management physicians and anti-aging clinics offer the best HCG Diet Weight Loss programs. HCG and The HCG Diet can be ideal for helping men and women lose weight quickly. Find out more information about HCG, HCG Injections, HCG Therapy, HCG Drops, HCG Kits, and HCG Diet plan – The HCG Diet.

Anti-Aging Therapeutics, Hormone Replacement Therapies, HGH, Aging and World Health Org

Anti-Aging Therapeutics Seminars, HGH and Hormone Replacement Therapy Information, Biomarkers for Aging

The evening workshop entitled Anti-Aging Therapeutics: The Anti-Aging Triad will take place in Orlando, Florida, April 8 at 6:30pm all attendees and vendors are welcome to attend. It is my intention to address modern concepts in anti-aging therapeutics, with a specific focus on what I have termed the Anti-Aging Triad of telomeres, stem cells and calorie restriction.

The Anti-Aging Triad is the title of my new book which will be launched at the April meeting and is available on an international basis. In the evening symposium I shall invite guest comments and short presentations. This will give a balanced perspective. It is my intention to express opinions on the real future of anti-aging medicine which is becoming increasingly evidence-based. Anti-aging medicine seeks evidence-based proposals to promote longevity. I propose “a triad” of interventions that are key targets in the future of anti-aging medicine. These proposals will ultimately supersede current “band aid” anti-aging initiatives such as hormone replacement therapies or standard esthetic interventions.

In the last two decades there has been expanding scientific research on the importance of telomere shortening as a biomarker of aging; and a confirmation of the role of calorie restriction in the enhancement of average and maximum lifespan. Stem cell sciences are emerging with promise for the management of chronic disease, new methods for organ production and specific actions on longevity promotion.


Hormone Replacement Therapies – HGH – The Human Growth Hormone

HGH and Hormone Replacement Therapy with bio-identical hormones is a very important treatment program that can also promote optimal health and wellness in those men and women experiencing symptoms due to menopause in women and andropause hypogonadism (male menopause) in men. Bio-identical (BHRT) – hormone replacement therapy for men and women has become a very effective tool in the fight against low hormonal health symptoms and conditions caused by menopause and hypogonadism, the male menopause. A hormone treatment program that replaces low testosterone levels and low human growth hormone levels can have a positive impact on a person’s health and quality of life. HGH and Testosterone Clinics with physicians that are hormone specialists can prescribe hormone injections and HGH replacement injections as part of the hormone therapy program. For more information on the benefits of HGH Therapy, HGH Injections  and Human Growth Hormone Programs visit AAG Health Medical Clinic in Miami Florida. HGH Therapy: Human Growth Hormone Therapy Programs at AAG Health – Bioidentical HGH Treatment Therapies – www.aaghealth.com

Learn about HGH Therapies, HGH Clinics that offer Bio-Identical Human Growth Hormone and Somatropin rHGH Injectable Growth Hormone for male hormone replacement therapy and female menopause bio-identical hormone replacement HGH Clinic @ www.hghtherapy.com


Hormone Replacement for Men: Pros, Cons

Testosterone Hormone Replacement & HGH Injections


Testosterone Replacement May Lower Risk of Heart Disease, Diabetes, Death, but Long-Term Effects Unclear

By Kathleen Doheny
WebMD Health News Reviewed by Louise Chang, MD

June 18, 2008 — Testosterone replacement therapy can help older men deficient in the hormone reduce their risks of heart disease, diabetes, and death, according to new research presented this week at ENDO 08, the annual meeting of The Endocrine Society.

”The goal of testosterone treatment is to keep the levels within normal range,” says Farid Saad, director of scientific affairs for Bayer Schering Pharma in Berlin. Saad presented two of the studies at the meeting, held in San Francisco. Bayer Schering Pharma makes several testosterone products.

Low levels of testosterone are common with age, Saad says, occurring in about 18% of 70-year-olds. Low levels of testosterone, he says, are associated with the metabolic syndrome — a cluster of risk factors such as abnormal cholesterol and high blood pressure that boost risk of heart disease, stroke, and type 2 diabetes as well as other risks to health.

In the studies, Saad and his colleagues found that testosterone replacement therapy reduced the metabolic syndrome risk factors and did so in a similar way in all the age ranges studied.

Testosterone Replacement Therapy and Heart Disease Risks

In the first study, Saad’s team looked at 95 men, aged 34 to 69, with low levels of testosterone.

All had metabolic syndrome. Those who have this diagnosis must have three of five risk factors: increased waist circumference, low “good” cholesterol or HDL, high triglycerides, elevated blood pressure, and elevated blood sugar.

“We treated them for at least a year,” he tells WebMD. Every three months, they measured cholesterol, waist circumference, and other parameters.

The testosterone replacement was given as a long-acting injection, every three months. The same product is not yet available in the U.S., Saad says, although other types are.

Testosterone Replacement Therapy: Test Results

“We saw a consistent improvement of the parameters of metabolic syndrome,” Saad says. The men were not given a special diet or exercise program.

The supplemental testosterone reduced total cholesterol, “bad” LDL cholesterol, triglycerides, and body mass index while improving “good” HDL cholesterol. The men lost their pot bellies, Saad says. “What we see after 12 months is a reduction in two or three trouser sizes, three or four inches off the waist. We see a reduction by one-fourth to one-third of their total cholesterol.”

No adverse effects were reported, he says.

While hormone replacement therapy for women has been found to be associated with increased risks of heart disease and other problems, Saad doesn’t foresee that will be the case with testosterone replacement. “There are fundamental differences between hormone replacement in women and testosterone treatment in men,” he tells WebMD.

Testosterone Replacement Therapy: No Age Effects?

In a second study, Saad divided the same 95 men into three groups, based on age: less than 57, 57 to 63, and older than 63.

They found the older men and the younger men had similar improvement in their risk factors.

“There are some precautions with testosterone supplementation,” Saad tells WebMD. “We need to monitor the prostate.”

“It is well known that with prostate cancer, the cancer is usually dependent on testosterone. Prostate cancer is a slow-growing tumor.” Cancer of the gland must be ruled out before starting supplements, he says. He also advises routine prostate checkups while on treatment.

A test to monitor red blood cell formation, called a hematocrit, is needed, too. “Testosterone increases red blood cells,” he says. In excess, it can theoretically boost heart attack or stroke risk.

Testosterone and Death Risk

Low testosterone levels are associated with an increased risk of death, according to Robin Haring, a researcher from the Institute for Community Medicine at Ernst-Moritz-Arndt University in Griefswald, Germany, who presented the finding at the meeting.

He evaluated data on nearly 2,000 men, aged 20 to 79, who participated in the Study of Health in Pomerania, following them for seven years until August 2007. He noted testosterone levels, age, weight, smoking habits, and physical activity. The drugmaker Novo Nordisk partly funded the study.

During the follow-up, 226 men died. “Men with low testosterone have a more than twofold higher risk of death during the follow-up period,” he says.

They were more likely to die of cardiovascular disease and cancer, but not of other causes.

Testosterone Replacement Therapy: Long-Term Effects Unknown

Another researcher, Jane F. Reckelhoff, PhD, professor of physiology and biophysics at the University of Mississippi Medical Center in Jackson, offers a caveat about supplemental testosterone: “We don’t know what the long-terms effects are. The safety studies have not been done and they need to be done.”

She reviewed the studies for WebMD and has published on a review about testosterone supplements for the American Journal of Physiology Renal Physiology.

Her chief concerns: “Testosterone [in excess] can increase blood pressure and compromise kidney function.”

But an advocate of testosterone replacement therapy, Martin Miner, MD, co-director of the Men’s Health Center at the Miriam Hospital of Brown University in Providence, R.I., says the studies show that restoring testosterone when it is low improves metabolic syndrome factors and could help prevent type 2 diabetes and cardiovascular risks.

He agrees close monitoring of men on testosterone is needed. “Checking hematocrit, PSA (prostate-specific antigen), and lower urinary tract symptoms in men is vital to the management of testosterone replacement therapy,” he says

To learn more about Testosterone Replacement Therapy: Testosterone Replacement Therapy or Testosterone Replacement Therapy for Men

Visit a hormone clinic to learn about HRT Hormone Replacement Therapy and the many hormone physicians centers available: Hormone Clinic: HGH Hormone Treatment and Testosterone Replacement Therapy @ AAG Health Hormone Physician’s Center – www.aaghealth.com or Testosterone Replacement Therapy for Men

To learn more about HGH Growth Hormone Replacement Therapy: HGH: Growth Hormone Replacement Therapy @ HGHTherapy.com, HGH Hormone Clinic @ AAGHealth.com or HGH Injection @ HGHTherapy.com

Sleep, Hormones & Disease, HGH Growth Hormone

Don’t turn a blind eye to insomnia’s link with diseases and hormone health

by Ramya Kannan

If your grandmother put you to bed telling you that it is essential to sleep, because that is when children do their growing up, she was so right. It has been scientifically proved that at a certain stage of sound sleep, the growth hormone is secreted and gets to work on the body.

Sleep, Hormone Health and Preventing Disease Hormone Related Articles and News at HGHNews.us - www.hghnews.us

A rejuvenating spa

Sleep is also important because it is the time when the body heals itself, sets the pulse rate, respiration and heart beat in a more orderly manner, and allows the muscles to relax. Getting six hours of sleep every day is a rejuvenating spa experience all by itself.

However, loss of sleep leads to a number of psychosocial problems and more chronic medical problems in the long run, explains N. Ramakrishnan of Nithra Sleep Institute. The short-term problems that are common are irritability, memory loss, decreased alertness and attention span, apart from drowsiness during the day.

More complex or chronic medical problems can be caused – hypertension, diabetes, hormonal issues among young women, cardiac and cerebro-vascular complications. “The lack of sleep has an unknown impact on deposition of fat on walls of vessels, causing earlier heart attacks and strokes. It can also cause diabetes, and poor blood sugar control in known diabetics. In fact, we have tied up with some diabetes centres to study the issue more carefully,” Dr. Ramakrishanan explains.

M. Thirunavukarasu, president, Indian Psychiatric Society, and head of Psychiatry, SRM Medical College, says, “There is much evidence to support a strong correlation between insomnia and cardiovascular diseases. In particular, the step-by-step development of hypertension seems to be strikingly linked to the functioning of sleep in the human body,” he says.

Sleep allows the heart to slow down and the blood pressure to drop for a significant part of the day. Dr. Thirunavukarasu adds that blood pressure dips by an average of 10 –20 per cent during sleep, so shorter sleep durations increase 24-hour blood pressure and heart rate, which over time lead to elevated pressure levels.

Vicious cycle

March is being observed as Sleep Awareness Month, and campaigns during this period also indicate that there is a vicious cycle related to sleep. People tend to eat more or binge for various reasons, also because they want to be engaged outside the bedroom, Dr. Ramakrishnan says. This leads to weight gain, even obesity, and may lead to hypertension, diabetes and cardiac problems.

One of his patients, a male in his mid-40′s came with a sleeping problem that was never addressed.

He had hypertension for a decade, had an angiogram and angioplasty, chronic headaches and three road traffic accidents. He had been to cardiologists, neurologists and psychiatrists, in and out of hospital emergency rooms, and had seen 12 consultants before his sleep problem was diagnosed.

In fact, he adds, there are international guidelines that specify a specialist must check for sleep disorders if hypertension is not adequately controlled with two or medications. Dr. Ramakrishnan also says it is important to create the right circumstances for sleep.

“For instance, avoid looking at computer screens late at night. The cue for the body to sleep is darkness. If there is a bright light source (the monitor), the chances of melatonin secretion is low.”

Consult a human growth hormone doctor HGH Doctor from a reputable human growth hormone clinic HGH Clinic before administration of injectable HGH (Somatropin Injection for Hormone Replacement of GH - Hormone Replacement Therapy)

Human Growth Hormone HGH – [somatropin (rDNA origin) injection]

Human Growth Hormone in the form of Injectable HGH can help with Sleep and Insomnia

Learn more about HGH Therapy, the use of bio-identical hormones, melatonin and natural HGH supplements, increasing your hormone health, and how low human growth hormone levels can impact your sleep and sleep patterns. HGH Therapy and Human Growth Hormone Replacement Info or contact an HGH Doctor specializing in bio-identical HRT for growth hormone replacement therapy today – Contact an HGH Physician

If you are thinking of ordering hormone replacement therapy for HGH, consult a human growth hormone doctor HGH Doctor from a reputable human growth hormone clinic HGH Clinic before administration of injectable HGH (Somatropin Injection for Hormone Replacement of GH - Hormone Replacement Therapy)


HGH and Obesity

HGH and Obesity

The risk of death from all causes, including cardiovascular disease and cancer, increases with rising obesity in both men and women in all age groups, and the risk associated with a high BMI is greater for whites than for blacks (Calle et al 1999).

Obesity increases the risk of developing metabolic syndrome and coronary heart disease (Shirai 2004); type 2 diabetes (Mensah et al 2004); osteoarthritis of major load-bearing joints, such as the knee (Felson et al 1997); hypertension (high blood pressure); sleep apnea (periods of suspended breathing during sleep) (Wolk et al 2003); and gall bladder disease (Petroni 2000).
The International Agency for Research on Cancer has classified obesity as a critical causal risk factor for cancers of the colon, breast (postmenopausal women), endometrium, kidney (renal cell), and esophagus (adenocarcinoma) (Calle et al 2004).

A study reported in the Journal of the American Medical Association suggests that obesity causes 111,909 deaths annually (Flegal et al 2005), while epidemiological evidence shows that a lower body weight is associated with lower mortality risk (Stevens 2000). In the well-known Framingham Heart Study, risk of death increased by 1 percent for each extra pound (0.45 kg) of weight between age 30 and 42 and increased by 2 percent between age 50 and 62 (Solomon et al 1997; Kopelman 2000).

Essential fatty acids (omega-3) found in fish oils promote thermogenesis, the process by which foods are converted to heat. Because of this, the body burns calories instead of converting them into fat for storage (McCarty 1994). Another benefit of essential fatty acids is to make cell membranes more sensitive to the effects of insulin (Storlien et al 1986, 1987, 1996; Borkman et al 1993; Vessby et al 1994; Pan et al 1995). Continue Reading

HGH – the Human Growth Hormone helps with Weight Control and Fatty Tissue

Hormone replacement with Human Growth Hormone can help with metabolism and fat loss. HGH treatment for symptoms due to menopause or andropause makes fat loss and increasing lean muscle mass easier to accomplish when growth hormone levels are raised to more youthful levels.

HGH is a natural substance that is excreted by the pituitary glands in the human body and bio-identical hormone treatments naturally restore lost growth hormone from your body. As we age, the level of HGH our bodies produces decreases over time and loss of lean muscle, weight gain and fatty tissue increase. Human growth hormone medications drugs usually given in the form of injections helps to raise the levels of HGH closer to optimal levels aiding in metabolism, the ability to exercise and subsequent fat loss.

Human growth hormone works by increasing the amount of IGF-1 that your liver excretes. IGF-1 blocks insulin from transporting glucose to your body cells. After eating, the pancreas usually releases insulin in sufficient levels to convert carbohydrates into glucose. The body stores the glucose in fat cells to use for energy as needed. As HGH induced IGF-1 prevents excess insulin from transporting glucose to be stored, the body starts to burn more fat for energy.

HGH helps control weight gain and with fat loss as follows: Normally, we use the glucose our body stores for energy and only when that stored glucose is used up do we use the fat reserves. By blocking the use of glucose stores, the theory is that we can get significant fat loss.

Here of some HGH Facts regarding weight loss and HGH Therapy:

You lose weight during your active periods. Energy is used for all aspects of living.

HGH helps with metabolism it does not force your body to burn fat.

HGH works well with a low-carb healthy diet and nutritional foods to lose unwanted weight.

HGH, in addition to helping you lose weight can help you increase muscle density and develop definition.

Human growth hormone increases strength, energy, stamina and endurance allowing better recovery after exercise.

HGH Hormone Replacement Therapies – HGH Testosterone – The Human Growth Hormone – Bio-Identical Hormones – Injectable HGH

HGH – Human Growth Hormone, Testosterone and Bio-Identical Hormone Replacement Therapy with “bio-identical” natural hormones is an important medical treatment program that can also promote optimal health and wellness in those men and women experiencing symptoms due to menopause in women and andropause – male menopause in men. Bio-identical (BHRT) – hormone replacement therapy for men and women has become a very effective tool in age management, and the fight against low hormonal health symptoms and deficiency conditions caused by menopause and hypogonadism, the male form of menopause.

A hormone treatment program including human growth hormone injections, testosterone injections, testosterone gel or creams that replace low testosterone levels and bio-identical HGH injections that increase and raise low human growth hormone levels can have a positive impact on a person’s health, weight and quality of life. HGH and Testosterone Clinics with physicians that are hormone specialists can prescribe hormone injections and HGH hormone replacement injections as part of a bio-identical hormone therapy program. For more information on the benefits of HGH Therapy, HGH Injections and Human Growth Hormone Programs visit AAG Health Medical Clinic in Miami Florida. Human Growth Hormone Therapy Programs at AAG Health – Bioidentical HGH Treatment Therapies – www.aaghealth.com

Some benefits of Human Growth Hormone HGH

* Positive changes in body composition including obesity.
* Restore lost of sex drive, treat impotence or low libido.
* Promote healthy lipids and cholesterol in the blood.
* Improved muscle strength, mass and tone.
* Improved bone composition and healing.
* Increased energy and exercise capacity.
* Cardiovascular and immuno health.
* Psychological well-being and mood.

Learn about HGH Therapies, HGH Clinics that offer Bio-Identical Human Growth Hormone and Somatropin rHGH Injectable Growth Hormone for male hormone replacement therapy and female menopause bio-identical hormone replacement HGH Clinic @ www.hghtherapy.com and HGH

HGH Therapy – AAG Health is one of the Best HGH Clinic visit the Growth Hormone Doctor at www.aaghealth.com | HGH @ http://www.aaghealth.com HGH Therapy at AAG Health – www.aaghealth.com

HGH Therapy, Body Composition Analysis

HGH Therapy and a Healthy Body

The HGH Clinic AAG Health at Anti-Aging Group AAG Health discuss how Human Growth Hormone Replacement can improve a person’s health. They report that part of a successful HRT (Hormone Replacement Therapy) program is to create a holistic treatment plan that includes nutrition, diet and an exercise routine that minimizes body fat while maximizing lean muscle. A body composition machine can measure the fat to muscle ratios and provide a BMI, Body Composition analysis. Anti-Aging Group’s Body Composition Analysis Machine. The Anti-Aging Group at AAG Health has an online index tool Body Mass Index for Body Composition Analysis

The Anti-Aging Group AAG Health Human Growth Hormone Therapists - Body Muscle Mass Analysis

For more information on the benefits of HGH replacement therapy, you may contact the AAG Health Human Growth Hormone Therapists at AAG Health HGH Therapists

Screening plan to tackle male menopause

Tackling Male Menopause

Doctors have drawn up plans to screen older men for the male menopause, amid concerns that as many as one in five of the over-65′s may be affected. The existence of a male equivalent to the menopause is still controversial, but most experts agree that some men experience a crash in testosterone and hgh growth hormone that can leave them tired, depressed and lacking in libido.

The so-called “andropause” has also been linked to diabetes, obesity, erectile dysfunction, and in some cases can be treated with testosterone injections and human growth hormone replacement injections. Medical associations, including the European Association of Urology have issued guidelines recommending that men with type 2 diabetes and symptoms of testosterone deficiency be tested.

The screening is going to pick up a lot of men with low testosterone who previously would have been sat at home without their doctor investigating. Once a hormone deficiency has been detected, a man can seek out the proper medical treatment for replacing the androgen deficiency.

To learn more about the various hormone replacement therapy options for men, visit some of the leading authorities in the treatment of male hormone deficiency – Male Hormone Therapy for Androgen Deficiency or Testosterone Replacement Therapy for Men